We are committed to providing top-quality services, and we take great pride in our work. Check out the selected work samples below, which resulted from work by our consultants.

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Peer-reviewed publications: Writing samples​

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• Bender C et al. Evaluation of in vitro tools to predict the in vivo absorption of biopharmaceuticals following subcutaneous administration. J Pharm Sci.

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• Allmendinger A et al. Intraocular pressure and injection forces during intravitreal injection into enucleated porcine eyes. Eur. J. Pharm. Biopharm.

 

• Forsvall A et al. Prostate biopsy quality and patient experience with the novel Forsvall biopsy needle - a randomized controlled non-inferiority trial. Scand J Urol.

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• Forsvall A et al. Rate and characteristics of infection after transrectal prostate biopsy: a retrospective observational study. Scand J Urol. ​

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• Forsvall A et al. Evaluation of the Forsvall biopsy needle in an ex vivo model of transrectal prostate biopsy - a novel needle design with the objective to reduce the risk of post-biopsy infection. Scand J Urol.

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• Kriegel C et al. Pediatric safety of polysorbates in drug formulations. Children (Basel).

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Pre-print manuscript: Writing samples

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• Axelsson U et al. Evaluation of Iron Oxide Nanoparticles for Lymph Node Detection with Magnetomotive Ultrasound – A Pilot Study in Rats. BioRxiv.

 

Peer-reviewed publications: Editing samples

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• Tresse E et al. IFN‐β rescues neurodegeneration by regulating mitochondrial fission via STAT5, PGAM5, and Drp1. EMBO J.

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• Alique M et al. MicroRNA-126 regulates Hypoxia-Inducible Factor-1α which inhibited migration, proliferation, and angiogenesis in replicative endothelial senescence. Sci Rep.

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• Mellhammar L, et al. New, useful criteria for assessing the evidence of infection in sepsis research. Crit Care Explor.

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• Polland L, et al. In vivo gene expression profile of Haemophilus influenzae during human pneumonia. Microbiol Spectr.

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Clinical trials

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• Protocolized reduction of non-resuscitation fluids in septic shock (REDUSE trial), NCT06140147​​

 

The REDUSE trial is investigating whether restricting fluid administration improves outcomes compared to standard care in patients with septic shock.​

Principal investigator: Peter Bentzer, MD, PhD

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• Protocolized reduction of non-resuscitation fluids in septic shock feasibility trial, NCT05249088​​

 

This completed trial evaluated the feasibility of reducing fluid administration in septic shock patients to improve clinical outcomes.

Principal investigator: Peter Bentzer, MD, PhD​

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• PROlonged posterior PERicardial chest tube treatment to reduce rates of postoperative atrial fibrillation following cardiac surgery (PROPER trial)​​

 

The PROPER trial is a randomized, controlled, interventional multicenter trial to determine whether prolonged posterior pericardial chest tube treatment to evacuate pericardial blood reduces the number of cardiac surgery patients who experience postoperative atrial fibrillation. 

Principal investigator: Igor Zindovic, MD, PhD

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Selected grant applications

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• Sandra Lindstedt, GLUSorb study (Vetenskapsrådet;19,500,000 SEK)

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Websites

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• reduse-trial.com